Ligandrol (LGD-4033)


Anabolicum (LGD-4033) is a SARM (selective androgen receptor modulator) that is currently in preclinical trials by Ligand Pharmaceuticals. Hence the nickname Ligandrol. The hope is that it will one day replicate testosterone use, but with fewer side effects.   The fitness community has been using it the past few years to give them a performance advantage.

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How it works

Anabolicum (LGD 4033) works by binding to androgen receptors mostly in the bones and muscles.  When the attachment occurs, this boosts muscle building and prevents any sort of muscle wasting even when you are in a caloric deficit.   So far the studies are encouraging and have shown a tight bond with androgen receptors.  Unlike anabolic steroids, Ligandrol is SELECTIVE, so you will not get any androgenic activity outside the bones or muscles hence no negative side effects.


ligandrol benefits

A phase 1 trial study was done on Anabolicum (LGD4033) on 75 healthy male adults who were 20-50 years old.   The group used it, along with a placebo group, for 21 days (3 weeks).  The study monitored lean body mass, muscle strength, sex hormones, and cardio output using stairs.   The results showed zero adverse side effects vs. The placebo group.   There was suppression at a higher dose, but no where close to what anabolic steroids would cause.

They also found the higher the dosage, the more lean body mass increased, but the cool thing was there was zero fat gained.  So the mass added was pure lean muscle mass!

A second study was done on elderly patients who had suffered major injuries, such as a joint fracture.  It found that it sped up bone recovery density, and it can also prevent injuries from occuring.


Athletes have been very impressed by what they have experienced when using Anabolicum (LGD-4033).   This includes:

  1. Increased muscle mass
  2. Decrease of body fat
  3. Increase of strength
  4. Faster recovery
  5. Greater endurance
  6. Injury prevention
  7. Injury repair

User reviews

Studies are great, but skeptics argue it is in a controlled environment.  They want real world examples of what Anabolicum (LGD 4033) can do.  After scrolling fitness forums I came across user results and I wanted to share what they said.

Mike said he used Anabolicum (LGD 4033) after breaking his arm.  He ran 10mgs per day for 8 weeks, his doctor said he would need 3 months out of the gym to recover from such an injury.  He was back in the gym in half that time!

Connie said she wanted to recomp, which means lose body fat and gain muscle at the same time.  Her original body fat was 26% and she weighed 146 pounds.  She ran Anabolicum (LGD 4033) and Cardarine GW501516, followed a good diet, and trained 3-4X per week in the gym.  Her results after 12 weeks was impressive.  Her body fat dropped to 21% and her body weight went up 1 pound!  She says she went from benching 80 pounds to 110 pounds.

How to stack Ligandrol

Anabolicum (LGD 4033) is one of my favorite SARMS (selective androgen receptor modulators) because of its versatility.   You can run it solo at 10-20mgs per day, or you can stack it many different ways.  Here are my recommendations on how best to use for best results:


Users report outstanding results when using Ligandrol at 10mg per day, in conjunction with a calorie deficit diet, along with 20mgs per day of Cardarine GW501516.   This cycle is typically 12 weeks.


Those whose goals are to gain quality mass and have a tough time with appetite, will use Ligandrol at 10-20mgs per day with Nutrobal MK677 at 25-50mgs per day.  Users like to go 8-12 weeks on this stack.

Overall performance:

Anabolicum (LGD-4033) will give the user a boost in performance at a dosage of 10mgs per day along with Ostarine Ostabolic MK2866 at 25mgs per day.   You can go 12-16 weeks on this stack.

With a steroid stack:

You can use Ligandrol with your anabolic steroids to give you a boost in endurance, lean muscle and fat loss.  A simple 10-20mg a day is ample with any steroid stack.  By doing this you will increase results, without increasing side effects.

Advantage over steroids

Nobody has ever claimed Anabolicum (LGD4033) is stronger than anabolic steroids in terms of how much mass or strength you will gain.  However, it does have several advantages:

  • Is approximately 75% less suppressive than anabolic steroids
  • Does not convert to estrogen
  • Will not cause Dihydrotestosterone side effects like loss of head hair and enlarged prostate
  • Won’t strain the liver
  • Will not cause androgenic side effects like high blood pressure or aggression
  • Is not inflammatory
  • Will not dry your joints

Side effects

Because Anabolicum (LGD4033) is selective (as mentioned earlier) the side effects are minimal.   The only thing you need to worry about is mild suppression, which you can easily counter by using a mini-PCT (post cycle therapy) with Hcgenerate ES, at the conclusion of your cycle.

Users who report significant side effects on Ligandrol are using fake products, usually laced with toxic prohormones.  It is important to make sure you always purchase from an approved source.

Half-life and Doping

lgd-4033 (Ligandrol) doping caseAnabolicum (LGD4033) half-life is about 30 hours, so once a day dosing is adequate.

It is unclear the detectable time of this compound, but based on reports it is somewhere around 3-6 weeks.  It is considered a banned substance by the World Anti-Doping Agency (WADA), as well as college and professional sports leagues.  You should not use it in those instances because cheating is wrong.

There have been reports of athletes caught using it and they were punished.   Stevesmi reported the news last year of professional basketball player Joakim Noah being busted for using it  .   A University of Florida quarterback was also caught using it and suspended 1 year.

Where to buy

Anabolicum (LGD4033) is becoming more difficult to find due to crackdowns by credit card processors in the United States. As of now it is still legal, but in a grey area, so make sure you buy LGD-4033 from an approved source.  Sarms1.com and esarms.com sells real SARMS, so I highly recommend checking them out.


LGD4033 & M1-MK Bulking Stack


Lean Muscle Mass Gains


Strength Gains




Fat Loss


Boost Recovery

Cardarine (GW-501516)
Andarine (S4)
Stenabolic (SR9009)
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